Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi

Apr 3, 2026

MCIDT Affiliates Teresa O’Meara and Marcy Balunas with Trainees Faith A Davis, Joseph Krampen, Jackson Rapala, and Michael McFadden discover Candida albicans cell wall remodeling is induced by metabolites of common gastrointestinal bacteria, negatively affecting immune response and antifungal susceptibility.

Key Terms: Candida; fungal-bacterial interactions; cell wall remodeling