Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the U.S. throughout the Delta to Omicron Waves

May 7, 2024

Authors: Adam Lauring,

Through the CDC’s National SARS-CoV-2 Strain Surveillance Program, MCIDT’s Adam Lauring helped antigenically characterize Delta, Mu, and Omicron COVID-19 subvariants, developing a framework applicable to emerging variants to assess vaccine/antigen efficacy

Key Terms: COVID-19, Strains, Omicron

Weekly proportions of SARS-CoV-2 variants in the U.S. with underlying U.S. case counts (1 May 2021 to 1 September 2023). Percentage of SARS-CoV-2 variants in the U.S. (line graph, 0% to 100%) were assembled from all available U.S. sequencing surveillance data. Variants represent an aggregation of many individual pangolin lineages aliased under a major parental lineage designation and were labeled with different colors. U.S. Weekly case counts were obtained from HHS Protect and are summarized in the grey bar graph (right-side, dual Y-axis)