A new study from Aubree Gordon, Greg Hoy, Thomas Cortier, and Simon Cauchemez shows that high levels of antibodies targeting both neuraminidase (NA) and the hemagglutinin (HA) stalk of influenza A/H3N2 are linked not only to reduced susceptibility but also to lower infectivity in household transmission settings. This insight highlights the potential for future vaccines to focus on inducing broader immune responses that could both protect individuals and reduce onward spread of influenza.
Key Terms: Influenza A, Neuraminidase, Hemagglutinin stalk, Household transmission
