Transcription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements
Published on 8 September 2023 in the Journal of Virology
MCIDT Affiliate Dr. Alice Telesnitsky’s research shows HIV-1 employs diverse transcription start sites (TSSs) to craft two RNA 5´ isoforms with radically different structures and each with specific functions shaping the virus’s pathogenesis